In computing, a keyboard shortcut is a set of one or more keys that invoke a command in software or an operating system. They are typically an alternate means for invoking commands that would otherwise be accessible only through a menu, a mouse, or an aspect of the user interface. List of All Computer Keyboard shortcut keys. We collated a list of some of the most commonly used basic shortcut keys that work with almost all IBM compatible computers and software programs. We recommend that all users keep a good reference of these and to try to memorize them. Doing so will dramatically increase your productivity.